THO Complex 4 anticorps (AA 1-257)

N° du produit ABIN7599173

L’anticorps Lapin Polyclonal anti-THO Complex 4 a été validé pour WB, ELISA, IF, ICC et FACS. Il convient pour détecter THO Complex 4 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour THO Complex 4 anticorps (AA 1-257) (ABIN7599173)

Antigène: THO Complex 4 (THOC4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THO Complex 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-THO Complex 4 anticorps

Épitope: AA 1-257

Fonction: Anti-ALYREF Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ALYREF Antibody Picoband® (ABIN7599173). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ALYREF recombinant protein (Position: M1-S257).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bruhn, L., Munnerlyn, A., Grosschedl, R. ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCR-alpha enhancer function. Genes Dev. 11: 640-653, 1997. 2. Luo, M.-J., Zhou, Z., Magni, K., Christoforides, C., Rappsilber, J., Mann, M., Reed, R. Pre-mRNA splicing and mRNA export linked by interactions between UAP56 and Aly. Nature 413: 644-647, 2001. 3. Masuda, S., Das, R., Cheng, H., Hurt, E., Dorman, N., Reed, R. Recruitment of the human TREX complex to mRNA during splicing. Genes Dev. 19: 1512-1517, 2005.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur THO Complex 4

Antigène: THO Complex 4 (THOC4)

Autre désignation: ALYREF

Sujet:

Synonyms: Segment polarity protein dishevelled homolog DVL-3,Dishevelled-3,DSH homolog 3,DVL3,KIAA0208,

Background: Aly/REF export factor, also known as THO complex subunit 4 is a protein that in humans is encoded by the ALYREF gene. The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.

Poids moléculaire: 35 kDa

ID gène: 10189

UniProt: Q86V81